For patients who have had a cryptogenic stroke and have a patent foramen ovale (PFO), clinical trials have shown that they can benefit from PFO closure.2-4 The Amplatzer PFO occluder significantly lowers the risk of recurrent ischemic stroke, and furthermore it offers an excellent safety profile.1
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PFO
TRIALS REPRESENT A TURNING POINT:
Three
large clinical trials have confirmed the superiority of PFO closure to medical
management in reducing risk of stroke recurrence. 4 One study, the
RESPECT trial, 2 is notable for several reasons: